PUBLICATIONS
Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment. Kerk SA, Papagiannakopoulos T, Shah YM, Lyssiotis CA. Nat Rev Cancer. 2021 Jul 9. (PubMed)
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells. Schwartz AJ, Goyert JW, Solanki S, Kerk SA, Chen B, Castillo C, Hsu PP, Do BT, Singhal R, Dame MK, Lee HJ, Spence JR, Lakhal-Littleton S, Heiden MGV, Lyssiotis CA, Xue X, Shah YM. Nat Metab. 2021 Jun 21. (PubMed)
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.Devenport SN, Singhal R, Radyk MD, Taranto JG, Kerk SA, Chen B, Goyert JW, Jain C, Das NK, Oravecz-Wilson K, Zhang L, Greenson JK, Chen YE, Soleimanpour SA, Reddy P, Lyssiotis CA, Shah YM. JCI Insight. 2021 Jun 17:138835. (PubMed)
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron. Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM. J Clin Invest. 2021 Jun 15;131(12):e143691. (PubMed)
Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference. Babitt JL, Eisenga MF, Haase VH, Kshirsagar AV, Levin A, Locatelli F, Małyszko J, Swinkels DW, Tarng DC, Cheung M, Jadoul M, Winkelmayer WC, Drüeke TB; Conference Participants. Kidney Int. 2021 Jun;99(6):1280-1295. (PubMed)
Hypoxia via ERK Signaling Inhibits Hepatic PPARα to Promote Fatty Liver. Mooli RGR, Rodriguez J, Takahashi S, Solanki S, Gonzalez FJ, Ramakrishnan SK, Shah YM. Cell Mol Gastroenterol Hepatol. 2021 Mar 30;12(2):585-597. (PubMed)
Enterobactin induces the chemokine, interleukin-8, from intestinal epithelia by chelating intracellular iron. Saha P, Yeoh BS, Xiao X, Golonka RM, Abokor AA, Wenceslau CF, Shah YM, Joe B, Vijay-Kumar M. Gut Microbes. 2020 Nov 9;12(1):1-18. (PubMed)
Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer. Golla JP, Kandyliari A, Tan WY, Chen Y, Orlicky DJ, Thompson DC, Shah YM, Vasiliou V. Chem Biol Interact. 2020 Nov 1;331:109274. (PubMed)
Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine. Singhal R, Shah YM. J Biol Chem. 2020 Jul 24;295(30):10493-10505. (PubMed)
Impact of dietary manganese on experimental colitis in mice. Choi EK, Aring L, Das NK, Solanki S, Inohara N, Iwase S, Samuelson LC, Shah YM, Seo YA. FASEB J. 2020 Feb;34(2):2929-2943. (PubMed)
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